Emerging Infectious Diseases (Aug 2017)

Clonal Expansion of New Penicillin-Resistant Clade of Neisseria meningitidis Serogroup W Clonal Complex 11, Australia

  • Shakeel Mowlaboccus,
  • Keith A. Jolley,
  • James E. Bray,
  • Stanley Pang,
  • Yung Thin Lee,
  • Jane D. Bew,
  • David J. Speers,
  • Anthony D. Keil,
  • Geoffrey W. Coombs,
  • Charlene M. Kahler

DOI
https://doi.org/10.3201/eid2308.170259
Journal volume & issue
Vol. 23, no. 8
pp. 1364 – 1367

Abstract

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In Western Australia, Neisseria meningitidis serogroup W clonal complex 11 became the predominant cause of invasive meningococcal disease in 2016. We used core-genome analysis to show emergence of a penicillin-resistant clade that had the penA_253 allele. This new penicillin-resistant clade might affect treatment regimens for this disease.

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