Prostate multi-parametric magnetic resonance imaging appearance of diffuse adenosis of the peripheral zone (DAPZ)

Avanka W. Lowe; Katarzyna J. Macura; Max Kates; Tamara Lotan; Michael C. Haffner; Steven P. Rowe

Urology Case Reports (Nov 2022)

Prostate multi-parametric magnetic resonance imaging appearance of diffuse adenosis of the peripheral zone (DAPZ)

Avanka W. Lowe,
Katarzyna J. Macura,
Max Kates,
Tamara Lotan,
Michael C. Haffner,
Steven P. Rowe

Affiliations

Avanka W. Lowe: The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Katarzyna J. Macura: The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Max Kates: The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Tamara Lotan: Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
Michael C. Haffner: Department of Pathology, University of Washington School of Medicine, Seattle, WA, USA
Steven P. Rowe: The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA; The James Buchanan Brady Urological Institute and Department of Urology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Corresponding author. The Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, 600 N. Wolfe St., Baltimore, MD 21287, USA.

Journal volume & issue: Vol. 45
p. 102178

Abstract

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Imaging specialists must recognize potential mimics of prostate cancer (PCa) on multi-parametric magnetic resonance imaging (mpMRI). We describe the appearance of diffuse adenosis of the peripheral zone (DAPZ) on mpMRI. The features of DAPZ parallel those of diffuse PCa, with low signal on T2-weighted images, rapid enhancement on dynamic contrast-enhanced sequences, and restricted diffusion. DAPZ is typically encountered in younger men with elevated prostate specific antigen (PSA) levels and portends an increased risk of the development of PCa. Recognition of the imaging appearance of DAPZ may reassure patients with concordant pathologic findings and may aid in selecting patients for follow-up.

Published in Urology Case Reports

ISSN: 2214-4420 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the genitourinary system. Urology
Website: http://www.urologycasereports.com/

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