OVARIAN AND UTERINE CHANGES INDUCED BY BROMOCRIPTINE INJECTION TO PSEUDOPREGNANT RATS

Abstract

Administration of bromocriptine (100 g) to rats on day 7 of pseudopregnancy (P.P.) caused a marked reduction in P.P. length associated with a significant reduction in ovarian weight and an increase in uterine weight. Structural changes included: a marked increase in the percentage of both antral follicles and atretic corpora lutea, endometrial lining height, stromal and myometrial thickness. The results reaffirm prolactin role in maintaining rat luteal function.

Keywords

• Rats
• Bromocriptine
• Uterine
• Prolactin