Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

Stratis Tzoumas; Antonio Nunes; Ivan Olefir; Stefan Stangl; Panagiotis Symvoulidis; Sarah Glasl; Christine Bayer; Gabriele Multhoff; Vasilis Ntziachristos

doi:10.1038/ncomms12121

Nature Communications (Jun 2016)

Eigenspectra optoacoustic tomography achieves quantitative blood oxygenation imaging deep in tissues

Stratis Tzoumas,
Antonio Nunes,
Ivan Olefir,
Stefan Stangl,
Panagiotis Symvoulidis,
Sarah Glasl,
Christine Bayer,
Gabriele Multhoff,
Vasilis Ntziachristos

Affiliations

Stratis Tzoumas: Institute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München
Antonio Nunes: Institute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München
Ivan Olefir: Institute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München
Stefan Stangl: Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München
Panagiotis Symvoulidis: Institute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München
Sarah Glasl: Institute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München
Christine Bayer: Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München
Gabriele Multhoff: Department of Radiation Oncology, Klinikum rechts der Isar, Technische Universität München
Vasilis Ntziachristos: Institute of Biological and Medical Imaging (IBMI), Helmholtz Zentrum München

DOI: https://doi.org/10.1038/ncomms12121
Journal volume & issue: Vol. 7, no. 1
pp. 1 – 10

Abstract

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Spectral corruption impedes imaging of blood oxygen saturation. Here Tzoumas et al.describe light fluence in the spectral domain and introduce eigenspectra Multispectral Optoacoustic Tomography to account for wavelength-dependent light attenuation and estimate blood oxygen saturation within deep tissue.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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