A comprehensive diffusion MRI dataset acquired on the MGH Connectome scanner in a biomimetic brain phantom
Qiuyun Fan,
Aapo Nummenmaa,
Barbara Wichtmann,
Thomas Witzel,
Choukri Mekkaoui,
Walter Schneider,
Lawrence L. Wald,
Susie Y. Huang
Affiliations
Qiuyun Fan
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, MA, United States; Corresponding author.
Aapo Nummenmaa
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, MA, United States
Barbara Wichtmann
Computer Assisted Clinical Medicine, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany
Thomas Witzel
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, MA, United States
Choukri Mekkaoui
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, MA, United States
Walter Schneider
Learning Research and Development Center, University of Pittsburgh, Pittsburgh, PA, United States
Lawrence L. Wald
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, MA, United States; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States
Susie Y. Huang
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, MA, United States; Harvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States
We provide a comprehensive diffusion MRI dataset acquired with a novel biomimetic phantom mimicking human white matter. The fiber substrates in the diffusion phantom were constructed from hollow textile axons (“taxons”) with an inner diameter of 11.8±1.2 µm and outer diameter of 33.5±2.3 µm. Data were acquired on the 3 T CONNECTOM MRI scanner with multiple diffusion times and multiple q-values per diffusion time, which is a dedicated acquisition for validation of microstructural imaging methods, such as compartment size and volume fraction mapping. Minimal preprocessing was performed to correct for susceptibility and eddy current distortions. Data were deposited in the XNAT Central database (project ID: dMRI_Phant_MGH).
