599 Single-agent safety and activities of target-preserving anti-CTLA-4 antibody gotistobart (ONC-392/BNT316) in PD-(L)1 resistant metastatic NSCLC and population PK analysis in patients with solid tumors

• Yang Liu,
• Dan Chen,
• Mark Goldstein,
• John Yang,
• Mei Tang,
• Rohit Joshi,
• David Carbone,
• Siwen Hu-Lieskovan,
• Zihai Li,
• Tianhong Li,
• Meredith McKean,
• Kai He,
• Julio Peguero,
• Pan Zheng,
• Hung-Yen Chou,
• Edward Arrowsmith,
• John Hamm,
• AIwu He,
• Satish Shah,
• Alexander I Spira,
• Rama Balaraman,
• Adriana millillo-Naranine

Affiliations

Yang Liu

Department of Emergency Medicine, Tianjin Medical University General Hospital, Tianjin, China

Dan Chen

1 Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Ministry of Education-Shanghai Key Laboratory of Children’s Environmental Health, Shanghai, China

Mark Goldstein

2 NCH Physician Group, Naples, Florida, USA

John Yang

19JP Global Pharma LLC, Rockville, MD, USA

Mei Tang

Department of Rheumatology and Immunology, Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China

Rohit Joshi

Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia

David Carbone

Aff2 grid.152326.10000000122647217Vanderbilt University Nashville TN USA

Siwen Hu-Lieskovan

Department of Oncology, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA

Zihai Li

Department of Medicine, Division of Hematology/Oncology, Ohio State Wexner Medical Center, Columbus, Ohio, USA

Tianhong Li

Aff98 grid.27860.3b0000000419369684University of California Davis Comprehensive Cancer Center Sacramento CA USA

Meredith McKean

Aff6 0000 0001 2291 4776grid.240145.6Division of Cancer MedicineUniversity of Texas MD Anderson Cancer Center 77030 Houston TX USA

Kai He

2 Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA

Julio Peguero

8Oncology Consultants, P.A., Houston, Texas, USA

Pan Zheng

Division of Immunotherapy, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, USA

Hung-Yen Chou

1OncoC4, Inc., Rockville, MD, USA

Edward Arrowsmith

Sarah Cannon Research Institute/Tennessee Oncology, PLLC, Chattanooga, Tennessee, USA

John Hamm

11Norton Healthcare, Louisville, KY, USA

AIwu He

3Georgetown University, Washington DC, USA

Satish Shah

2Pennsylvania Cancer Specialists, Gettysburg, PA, USA

Alexander I Spira

2Next Oncology, Fairfax, VA, USA

Rama Balaraman

6Florida Cancer Affiliates-US Oncology, Ocala, FL, USA

Adriana millillo-Naranine

10Memorial Cancer Institute, Pembroke, FL, USA