Bioprinted Membranes for Corneal Tissue Engineering: A Review
Amin Orash Mahmoud Salehi,
Saeed Heidari-Keshel,
Seyed Ali Poursamar,
Ali Zarrabi,
Farshid Sefat,
Narsimha Mamidi,
Mahmoud Jabbarvand Behrouz,
Mohammad Rafienia
Affiliations
Amin Orash Mahmoud Salehi
Department of Chemistry and Nanotechnology, School of Engineering and Science, Tecnologico de Monterrey, Monterrey 64849, NL, Mexico
Saeed Heidari-Keshel
Department of Tissue Engineering and Applied Cell Sciences, School of Advanced Technologies in Medicine, Shahid Beheshti University of Medical Sciences, Tehran 1434875451, Iran
Seyed Ali Poursamar
Biosensor Research Center, Isfahan University of Medical Sciences, Isfahan 8174673441, Iran
Ali Zarrabi
Department of Biomedical Engineering, Faculty of Engineering and Natural Sciences, Istinye University, Istanbul 34396, Turkey
Farshid Sefat
Department of Biomedical and Electronics Engineering, School of Engineering, University of Bradford, Bradford BD7 1DP, UK
Narsimha Mamidi
Department of Chemistry and Nanotechnology, School of Engineering and Science, Tecnologico de Monterrey, Monterrey 64849, NL, Mexico
Mahmoud Jabbarvand Behrouz
Translational Ophthalmology Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran 1985717443, Iran
Mohammad Rafienia
Biosensor Research Center, Isfahan University of Medical Sciences, Isfahan 8174673441, Iran
Corneal transplantation is considered a convenient strategy for various types of corneal disease needs. Even though it has been applied as a suitable solution for most corneal disorders, patients still face several issues due to a lack of healthy donor corneas, and rejection is another unknown risk of corneal transplant tissue. Corneal tissue engineering (CTE) has gained significant consideration as an efficient approach to developing tissue-engineered scaffolds for corneal healing and regeneration. Several approaches are tested to develop a substrate with equal transmittance and mechanical properties to improve the regeneration of cornea tissue. In this regard, bioprinted scaffolds have recently received sufficient attention in simulating corneal structure, owing to their spectacular spatial control which produces a three-cell-loaded-dimensional corneal structure. In this review, the anatomy and function of different layers of corneal tissue are highlighted, and then the potential of the 3D bioprinting technique for promoting corneal regeneration is also discussed.
