A study on changes in choroidal thickness in antenatal women with pregnancy-induced hypertension using spectral-domain-optical coherence tomography

Abstract

Aim: To evaluate the choroidal thickness using spectral-domain optical coherence tomography (SD-OCT) in antenatal women with pregnancy induced hypertension. Methods and Material: In this observational study 100 eyes of 50 pregnant women with pregnancy induced hypertension were included and compared with age matched non- pregnant women. Retinal SD OCT scan was done. The choroidal thickness at the fovea, 500 μm nasal and temporal to the fovea were measured manually. Statistical analysis used: Unpaired T test was used. Results: The mean choroidal thickness in pregnant women with PIH was 346.23 μm and in normal non-pregnant women it was 296.16 μm. In Multigravida with PIH (317.91 μm) the choroidal thickness was found to be less when compared with primigravida with PIH(359.53). All these results were statically significant. Conclusions: This study revealed that there was increase in choroidal thickness in pregnant women with PIH when compared to non-pregnant women. However there was a significant decrease in choroidal thickness in multigravida women with history of PIH and also the thickness of choroid decreased with increase in age.Further studies are needed to correlate choroidal blood flow and choroidal thickness in PIH mother.

Keywords

• choroidal thickness
• optical coherence tomography
• pregnancyinduced hypertension