Zhongguo cuzhong zazhi (Feb 2025)
肿瘤相关性缺血性卒中的发病机制研究进展 Research Progress on the Pathogenesis of Cancer-Associated Ischemic Stroke
Abstract
肿瘤相关性缺血性卒中是肿瘤患者常见且复杂的并发症,表现为多部位血栓形成和多发性脑梗死,其发病机制非常复杂。本文对肿瘤直接作用、高凝状态、非细菌性血栓性心内膜炎、肿瘤相关检查或治疗等肿瘤相关性缺血性卒中的发病机制进行了综述,以期为肿瘤患者制订个体化抗癌和卒中预防策略提供参考。 Abstract: Cancer-associated ischemic stroke (CAIS) is a common and complex complication in tumor patients, manifesting as multi-site thrombosis and multiple cerebral infarctions. Its pathogenesis is very complicated. This article reviewed the pathogenesis of CAIS, including the direct effects of tumors, hypercoagulabale state, nonbacterial thrombotic endocarditis, and tumor-related examinations or treatments, aiming to provide references for the formulation of individualized anti-cancer and stroke prevention strategies for tumor patients.
Keywords