مجلة كلية الطب (Jul 2008)

Correlation between some immunological parameters and clinical presentation in RA patients

  • Nahida R. Abbas,
  • Eman Sh. AL- Obeidy,
  • Samira N. AL- Naim,
  • Ali E. Kadim

DOI
https://doi.org/10.32007/1288%g235-240
Journal volume & issue
Vol. 50, no. 2

Abstract

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Background: Complement (C) & CRP in patients with Rheumatoid arthritis (RA)'could be trigger disease activity. Aim: To study the correlation between C, CRP, IgM,, IgG, IgA & some clinical presentation in RA patients. Methods: Latex agglutination test(AG) & single radial immunoassay(SRIA) were used to asses CRP, IgMJgGJgA,, C, in 74 patients with RA. Results: IgA & IgG were significantly increased, while the mean ofC3, C4 were slightly elevated in RA patients . Conclusion: There is correlation between IgG and IgM with joint deformity and joint swelling respectively, while C3 was showed statistically significant P<0.01 with joint stiffness, joint swelling and Rheumatoid nodule, where as CRP was statistically significant P<0.01withjoint swelling.. Key words : RA.C.CRP, IgM, IgG, IgA, SRI A, AG.

Keywords