卒中与酒精使用所致障碍相关性的研究进展 Research Progress on Correlation between Stroke and Alcohol Use Disorder

Abstract

摘要： 酒精使用所致障碍作为全球第五大风险因素，是卒中预防的重要内容。近年来大量流行病学和临床研究显示，酒精使用与卒中之间存在相关性，酒精可通过多种途径影响心脑血管健康，从而引发卒中甚至死亡。同时也有研究显示，酒精使用与卒中之间或许存在不同的关联性，轻度饮酒可能是心脑血管的保护因素，中重度饮酒可能会诱发、加重卒中。本文分析了卒中合并酒精使用所致障碍的流行现状，对酒精使用所致障碍影响卒中发病的可能机制进行综述，同时总结了酒精摄入监测生物标志物和酒精使用所致障碍的治疗方式，以期进一步探讨卒中与酒精使用所致障碍之间的相关性，为临床诊疗提供思路。 Abstract: Alcohol use disorder, as the fifth largest risk factor worldwide, is an important component of stroke prevention. In recent years, a large number of epidemiological and clinical studies have shown that there is a correlation between alcohol and stroke. Alcohol can affect cardiovascular and cerebrovascular health through various ways, resulting in stroke and even death. At the same time, some studies have shown that there may be different associations between alcohol and stroke, light drinking may be a cardiovascular and cerebrovascular protective factor, and moderate and heavy drinking may induce and aggravate stroke. This paper analyzed the current prevalence of stroke complicated with alcohol use disorder, reviewed the possible pathogenesis of alcohol use disorder affecting the incidence of stroke, and summarized alcohol intake monitoring biomarkers and treatments related to alcohol use disorder, in order to further explore the correlation between stroke and alcohol use disorder and provide ideas for clinical diagnosis and treatment.

Keywords

• 卒中
• 酒精使用所致障碍
• 相关性
• 综述
• stroke
• alcohol use disorder
• correlation; review