Respiratory disorders in patients with polymyositis/dermatomyositis

Abstract

Idiopathic inflammatory myopathies (IIM) are rare disorders characterized by inflammatory lesions in skeletal muscles. These diseases include polymyositis (PM), dermatomyositis (DM), and inclusion body myositis, which exhibit clinicoimmunological heterogeneity and give different response to therapy. The most frequent manifestation in PM/DM patients is respiratory system dysfunction. The developing respiratory disorders are varied and may outpace the presentation of muscle pathology.

Keywords

• idiopathic inflammatory myopathies
• polymyositis
• dermatomyositis
• antisynthetase syndrome
• glucocorticoids