A Rare Case of Retroperitoneal Liposarcoma and Castleman’s Disease

Abstract

Retroperitoneal liposarcoma is a malignant mesenchymal tumour. The incidence is rare and early diagnosis is difficult as they present with non specific symptoms. A 55-year-old male patient, presented to General Surgery Department with complaints of abdominal swelling since two months and discomfort for three to four months. Abdominal examination revealed a mass, soft to firm in consistency with restricted mobility, was palpated in right quadrants. A clinical diagnosis of soft tissue tumour was made. Abdominopelvic computed tomography (CT) scan was performed showing a well-defined circumscribed, low-attenuated mass of retroperitoneal origin crossing midline and significantly displacing the intestinal loops, right grade 2 hydronephrosis and was compressing on inferior vena cava posteriorly. The patient underwent a resection surgery of the lesion and the histopathological examination showed a well-differentiated liposarcoma and Castleman’s disease. These tumours are generally resistant to radiotherapy and/or chemotherapy. Thus the major prognostic factor related to survival is resection with tumour-free margins that includes the tumour as well as adjacent structures showing infiltration.

Keywords

• lymphoproliferative
• mesenchymal tumour
• sarcoma
• soft tissue