3Y-TZP/Ta Biocermet as a Dental Material: An Analysis of the In Vitro Adherence of Streptococcus Oralis Biofilm and an In Vivo Pilot Study in Dogs
Anton Smirnov,
Oleg Yanushevich,
Natella Krikheli,
Nestor Washington Solis Pinargote,
Pavel Peretyagin,
Sergey Grigoriev,
Luis Alou,
David Sevillano,
Roberto López-Piriz,
Francisco Guitian,
José Florindo Bartolomé
Affiliations
Anton Smirnov
Spark Plasma Sintering Research Laboratory, Moscow State University of Technology “STANKIN”, Vadkovsky per. 1, Moscow 127055, Russia
Oleg Yanushevich
Scientific Department, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Delegatskaya St., 20, p. 1, Moscow 127473, Russia
Natella Krikheli
Scientific Department, A.I. Evdokimov Moscow State University of Medicine and Dentistry, Delegatskaya St., 20, p. 1, Moscow 127473, Russia
Nestor Washington Solis Pinargote
Spark Plasma Sintering Research Laboratory, Moscow State University of Technology “STANKIN”, Vadkovsky per. 1, Moscow 127055, Russia
Pavel Peretyagin
Spark Plasma Sintering Research Laboratory, Moscow State University of Technology “STANKIN”, Vadkovsky per. 1, Moscow 127055, Russia
Sergey Grigoriev
Spark Plasma Sintering Research Laboratory, Moscow State University of Technology “STANKIN”, Vadkovsky per. 1, Moscow 127055, Russia
Luis Alou
Microbiology Department, School of Medicine, Universidad Complutense, Avda. Complutense s/n, 28040 Madrid, Spain
David Sevillano
Microbiology Department, School of Medicine, Universidad Complutense, Avda. Complutense s/n, 28040 Madrid, Spain
Roberto López-Piriz
Instituto de Cirugía Oral Avanzada-ICOA, Calle de Fray Luis de León, 14, 28012 Madrid, Spain
Francisco Guitian
Instituto de Materiales, iMATUS-USC, Santiago de Compostela, Avenida do Mestre Mateo 25, 15782 La Coruña, Spain
José Florindo Bartolomé
Instituto de Ciencia de Materiales de Madrid (ICMM), Consejo Superior de Investigaciones Científicas (CSIC), Campus de Cantoblanco, Calle Sor Juana Inés de la Cruz 3, 28049 Madrid, Spain
The surface adhesion of bacterial cells and the in vivo biocompatibility of a new ceramic–metal composite made of zirconium dioxide and tantalum were evaluated. Within the framework of an in vitro study using the crystal violet staining and colony counting methods, a relatively similar adhesion of Streptococcus oralis to the 3Y-TZP/Ta biocermet (roughness Ra = 0.12 ± 0.04 µm) and Ti-Al6-V4 titanium alloy (Ra = 0.04 ± 0.01 µm) was found. In addition, in an in vivo preliminary study focused on the histological analysis of a series of rods implanted in the jaws of beagle dogs for a six-month period, the absence of any fibrous tissue or inflammatory reaction at the interface between the implanted 3Y-TZP/Ta biocermets and the new bone was found. Thus, it can be concluded that the developed ceramic–metal biocomposite may be a promising new material for use in dentistry.
