PATHOGENETIC SIGNIFICANCE OF LYMPHOCYTE-TO-PLATELET ADHERENCE

Abstract

Abstract. The data from literature and own results of the authors are presented in the article, concerning interactions between lymphocytes and platelets. It was demonstrated that the adherence of blood platelets to lymphocytes seems to be a reliable and highly informative test, which provides data on the state of immunity and haemostatic system. Sufficient section of this article deals with a role of adhesion molecules and cytokines in regulation of the lymphocyte-to-platelet adherence.Recent works are presented about implementation of anti-adhesive molecules into treatment of various diseases that are accompanied by development of thromboembolic diseases.

Keywords

• lymphocytes
• platelets
• adhesion molecules
• cytokines