Drug Design, Development and Therapy (Jun 2022)
Research Progress of Liujunzi Decoction in the Treatment of Tumor-Associated Anorexia
Abstract
Xipei Wu, Yongzhao Dai, Ke Nie School of Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou, People’s Republic of ChinaCorrespondence: Ke Nie, School of Chinese Materia Medica, Guangdong Pharmaceutical University, Guangzhou, 510006, People’s Republic of China, Email [email protected]; [email protected]: Tumor-associated anorexia, mainly including cancerous anorexia and chemotherapy-induced anorexia, severely reduces the life quality of cancer patients but lacks of effective control until now. Liujunzi decoction (LJZD), a classical tonifying formula in traditional Chinese medicine, has promising effect in preventing and treating many kinds of anorexia. A growing number of evidence showed that LJZD is able to improve tumor-associated anorexia. Up to March 2022, a total of 58 articles studying LJZD or Rikkunshito (the name of LJZD in Japanese herbal medicine) in the treatment of tumor-associated anorexia are searched out in PubMed. This paper summarizes the effect of LJZD in ameliorating tumor-associated anorexia, in order to provide a theoretical basis for the clinical application of LJZD in treating tumor-associated anorexia, laying foundation for further research.Keywords: Liujunzi decoction, tumor-associated anorexia, review
