Methodical approaches to teaching age features of "Connective tissue proper" in a lecture course and on a practical training on histology

Abstract

Understanding of cellular and tissue mechanisms which are the cornerstone of age changes of connective tissue allows to create at students of the first courses idea of realization of trophic, mechanical, protective, adaptive functions during various age periods and to create complete approach to assessment of integrative connective tissue of function during various age periods. In work cytotopographical classification of connective tissue proper is provided, characteristic of a cytogenesis and cytophysiology of cells of a fibroblastic differon in age aspect is given, are provided a morph – functional changes of connective tissue in the prenatal and post-natal periods of an ontogenesis. Special attention is devoted to morphogenetic changes of cells of a fibroblastic differon and intercellular matrix of fibrous connective tissue when aging. Age changes of connective tissue are defined by reduction of number and change of a ratio between cell of a fibroblastic differon, decrease in their proliferative and synthetic activity that is followed by changes of quantitative and qualitative structure of an intercellular matrix and it integrative – buffer properties.

Keywords

• гістологія
• власне сполучні тканини
• фібробласти
• міжклітинний матрикс
• вікові зміни