Journal of General and Family Medicine (Jul 2020)

Asymptomatic pulmonary penicilliosis with a lung mass in an HIV‐infected patient

  • Masashi Nishikubo,
  • Asako Doi,
  • Hiroshi Takegawa,
  • Daisuke Yamashita,
  • Junichiro Ohira,
  • Hiroaki Nishioka

DOI
https://doi.org/10.1002/jgf2.325
Journal volume & issue
Vol. 21, no. 4
pp. 152 – 154

Abstract

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Abstract Penicillium marneffei (Talaromyces marneffei) infection sometimes occurs in HIV‐infected patients in South‐East Asia. However, reports on asymptomatic cases are rare. Herein, we report a case of a 27‐year‐old Burmese HIV‐positive woman with pulmonary penicilliosis. Chest radiography showed a lung mass; however, the patient did not have any respiratory symptoms. Cultures of bronchoalveolar lavage and lung tissue grew P marneffei. The patient was diagnosed with penicilliosis and successfully treated with amphotericin B and itraconazole. Our findings suggest that P marneffei infection should be considered in the differential diagnosis of a lung mass in HIV‐infected patients, even when asymptomatic for respiratory symptoms.

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