Системные гипертензии (Mar 2014)

Practical aspects of fixed combinations in the treatment of hypertension

  • M Yu Ogarkov,
  • M N Baranova,
  • A E Skripchenko

Journal volume & issue
Vol. 11, no. 1
pp. 22 – 25

Abstract

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Hypertension is a leading cause of heart attacks and strokes. Reaching target blood pressure (BP) in hypertension is the main condition optimization outlook for cardiovascular morbidity and mortality. To solve this problem in a substantial portion of patients, who are in need of antihypertensive drugs, wherein 70-80% of the target blood pressure can be achieved using a combination therapy. Fixed combinations of antihypertensive drugs increase treatment compliance and provide better organ protection. The new fixed combination of highly selective β-blocker bisoprolol and the calcium antagonist amlodipine can achieve target BP levels in 82,5% of patients with a minimum frequency of side effects.

Keywords