Multiparametric Prostate MRI Accuracy of Prostate Imaging Reporting and Data System (v2.1) Scores 4 and 5: The Influence of Image Quality According to the Prostate Imaging Quality Score

Andrea Fuschi; Paolo Pietro Suraci; Antonio Luigi Pastore; Yazan Al Salhi; Paola Capodiferro; Silvio Scalzo; Onofrio Antonio Rera; Fabio Maria Valenzi; Michele Di Dio; Pierluigi Russo; Mohammad Talal Al-Zubi; Saddam Al Demour; Samer Fathi Al-Rawashdah; Giorgio Mazzon; Davide Bellini; Iacopo Carbone; Vincenzo Petrozza; Giorgio Bozzini; Alessandro Zucchi; Matteo Pacini; Giorgia Tema; Cosimo De Nunzio; Antonio Carbone; Marco Rengo

doi:10.3390/jcm13133785

Journal of Clinical Medicine (Jun 2024)

Multiparametric Prostate MRI Accuracy of Prostate Imaging Reporting and Data System (v2.1) Scores 4 and 5: The Influence of Image Quality According to the Prostate Imaging Quality Score

Andrea Fuschi,
Paolo Pietro Suraci,
Antonio Luigi Pastore,
Yazan Al Salhi,
Paola Capodiferro,
Silvio Scalzo,
Onofrio Antonio Rera,
Fabio Maria Valenzi,
Michele Di Dio,
Pierluigi Russo,
Mohammad Talal Al-Zubi,
Saddam Al Demour,
Samer Fathi Al-Rawashdah,
Giorgio Mazzon,
Davide Bellini,
Iacopo Carbone,
Vincenzo Petrozza,
Giorgio Bozzini,
Alessandro Zucchi,
Matteo Pacini,
Giorgia Tema,
Cosimo De Nunzio,
Antonio Carbone,
Marco Rengo

Affiliations

Andrea Fuschi: Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Paolo Pietro Suraci: Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Antonio Luigi Pastore: Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Yazan Al Salhi: Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Paola Capodiferro: Department of Radiological, Oncological and Pathological Sciences, Academic Diagnostic, Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Silvio Scalzo: Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Onofrio Antonio Rera: Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Fabio Maria Valenzi: Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Michele Di Dio: Division of Urology, Department of Surgery, Annunziata Hospital, 87100 Cosenza, Italy
Pierluigi Russo: Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Rome, Italy
Mohammad Talal Al-Zubi: Department of Surgery, Division of Urology, School of Medicine, Yarmouk University, Irbid 21110, Jordan
Saddam Al Demour: Department of Special Surgery, Division of Urology, School of Medicine, The University of Jordan, Amman 11972, Jordan
Samer Fathi Al-Rawashdah: Department of Special Surgery, Urology Unit, School of Medicine, Mutah University, Karak 61710, Jordan
Giorgio Mazzon: Institute of Urology, University College Hospital, London NW12BU, UK
Davide Bellini: Department of Radiological, Oncological and Pathological Sciences, Academic Diagnostic, Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Iacopo Carbone: Department of Radiological, Oncological and Pathological Sciences, Academic Diagnostic, Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Vincenzo Petrozza: Pathology Unit, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Giorgio Bozzini: Division of Urology, Sant’Anna Hospital, San Fermo della Battaglia, 22042 Como, Italy
Alessandro Zucchi: Department of Urology, University of Pisa, 56126 Pisa, Italy
Matteo Pacini: Department of Urology, University of Pisa, 56126 Pisa, Italy
Giorgia Tema: Department of Urology, Sapienza University of Rome, Sant’Andrea Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy
Cosimo De Nunzio: Department of Urology, Sapienza University of Rome, Sant’Andrea Hospital, Via di Grottarossa 1035-1039, 00189 Rome, Italy
Antonio Carbone: Unit of Urology, Department of Medical-Surgical Sciences and Biotechnologies, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy
Marco Rengo: Department of Radiological, Oncological and Pathological Sciences, Academic Diagnostic, Imaging Division, I.C.O.T. Hospital, University of Rome Sapienza, Via F. Faggiana 1668, 04100 Latina, Italy

DOI: https://doi.org/10.3390/jcm13133785
Journal volume & issue: Vol. 13, no. 13
p. 3785

Abstract

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Purpose: The accuracy of multiparametric magnetic resonance imaging (mpMRI) heavily relies on image quality, as evidenced by the evolution of the prostate imaging quality (PI-QUAL) scoring system for the evaluation of clinically significant prostate cancer (csPC). This study aims to evaluate the impact of PI-QUAL scores in detecting csPC within PI-RADS 4 and 5 lesions. Methods: We retrospectively selected from our database all mpMRI performed from January 2019 to March 2022. Inclusion criteria were as follows: (1) mpMRI acquired in our institution according to the technical requirements from the PI-RADS (v2.1) guidelines; (2) single lesion scored as PI-RADS (v2.1) 4 or 5; (3) MRI-TBx performed in our institution; (4) complete histology report; and (5) complete clinical record. Results: A total of 257 male patients, mean age 70.42 ± 7.6 years, with a single PI-RADS 4 or 5 lesion undergoing MRI-targeted biopsy, were retrospectively studied. Of these, 61.5% were PI-RADS 4, and 38.5% were PI-RADS 5, with 84% confirming neoplastic cells. In high-quality image lesions (PI-QUAL ≥ 4), all PI-RADS 5 lesions were accurately identified as positive at the final histological examination (100% of CDR). For PI-RADS 4 lesions, 37 (23%) were negative, resulting in a cancer detection rate of 77% (95% CI: 67.51–84.83). Conclusions: The accuracy of mpMRI, independently of the PI-RADS score, progressively decreased according to the decreasing PI-QUAL score. These findings emphasize the crucial role of the PI-QUAL scoring system in evaluating PI-RADS 4 and 5 lesions, influencing mpMRI accuracy.

Published in Journal of Clinical Medicine

ISSN: 2077-0383 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/jcm

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