Indian Journal of Dermatology (Jan 2011)

Progeria in siblings: A rare case report

  • R Sowmiya,
  • D Prabhavathy,
  • S Jayakumar

DOI
https://doi.org/10.4103/0019-5154.87162
Journal volume & issue
Vol. 56, no. 5
pp. 581 – 582

Abstract

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Progeria, also known as Hutchinson-Gilford syndrome, is an extremely rare, severe genetic condition wherein symptoms resembling aspects of aging are manifested at an early age. It is an autosomal dominant disorder. It is not seen in siblings of affected children although there are very few case reports of progeria affecting more than one child in a family. Here we are presenting two siblings, a 14-year-old male and a 13-year-old female with features of progeria, suggesting a possible autosomal recessive inheritance.

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