Data in Brief (Sep 2015)

Data in support of in vivo studies of silk based gold nano-composite conduits for functional peripheral nerve regeneration

  • Suradip Das,
  • Manav Sharma,
  • Dhiren Saharia,
  • Kushal Konwar Sarma,
  • Monalisa Goswami Sarma,
  • Bibhuti Bhusan Borthakur,
  • Utpal Bora

DOI
https://doi.org/10.1016/j.dib.2015.05.020
Journal volume & issue
Vol. 4, no. C
pp. 315 – 321

Abstract

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In the present data article we report the in vitro and in vivo biocompatibility of fabricated nerve conduits described in Das et al. [1]. Green synthesised gold nanoparticles (GNPs) were evaluated for their cytotoxicity in rat Schwann cells (SCTM41). We also describe herein the adhesion and proliferation of Schwann cells over the nanofibrous scaffolds. Methods describing surgical implantation of conduits in a rat sciatic nerve injury model, confirming its accurate implantation as well as the porosity and swelling tendency of the nerve conduits are illustrated in the various figures and graphs.