Journal of Contemporary Brachytherapy (Nov 2016)

Successful treatment of a 67-year-old woman with urethral adenocarcinoma with the use of external beam radiotherapy and image guided adaptive interstitial brachytherapy

  • Jasmin Mujkanovic,
  • Kari Tanderup,
  • Mads Agerbæk,
  • Ulla Bisgaard,
  • Søren Høyer,
  • Jacob Christian Lindegaard,
  • Lars Fokdal

DOI
https://doi.org/10.5114/jcb.2016.63461
Journal volume & issue
Vol. 8, no. 5
pp. 434 – 437

Abstract

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Primary urethral cancer (PUC) is a very rare disease. This case report illustrates a successful treatment approach of a 67-year-old woman with a urethral adenocarcinoma selected for an organ preserving treatment with external beam radiotherapy (EBRT) and interstitial brachytherapy (BT) boost, using the GEC-ESTRO target concept originally designed for locally advanced cervical cancer (LACC). Treatment included EBRT with 45 Gy in 25 fractions followed by image guided adaptive interstitial BT (IGABT) with a pulsed-dose-rate (PDR) BT boost with 30 Gy in 50 hourly pulses. The D 90 for CTV HR was 79.1 Gy in EQD23. At 24 months follow-up, the patient was recurrence free and without treatment related side effects.

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