Prompting endogenous repair of brain injury: science fiction or reality?

Abstract

Abstract Drug-refractory forms of neurological diseases could find their next breakthrough therapy in non-pharmacological approaches to brain repair. Lentini et al. present the potential of in situ brain regeneration to address neurodegeneration in the epileptic brain.

Keywords

• Regenerative medicine
• In situ lineage conversion
• Mesial temporal lobe epilepsy with hippocampal sclerosis
• Epilepsy
• Neurodegenerative medicine
• Gene therapy