Microwave assisted synthesis of 2-pyridone and 2-pyridone based compounds

Abstract

2-Pyridones are important heterocyclic compounds that are widely used in medical chemistry, and their various derivatives have significant biological and medical applications. In this paper, the synthesis of 2-pyridones as well as 2-pyridone based compounds such as 2-quinolones using microwave assisted organic chemistry is reviewed. The review is divided in three parts. In the first part, microwave synthesis of 2-pyridones according to the type of condensation is discussed. In the second part, microwave assisted synthesis of 2-quionolones is listed. At the end of the review several examples of microwave synthesis of other 2-pyridone based compounds (ring fused N-substituted 2-pyridones) are given. [Projekat Ministarstva nauke Republike Srbije, br. 172013]

Keywords

• heterocyclic compounds
• medical chemistry
• microwave assisted organic chemistry
• 2-quinolone
• ring fused N-substituted 2-pyridones