Nature Communications (Feb 2018)
An ancient family of lytic polysaccharide monooxygenases with roles in arthropod development and biomass digestion
- Federico Sabbadin,
- Glyn R. Hemsworth,
- Luisa Ciano,
- Bernard Henrissat,
- Paul Dupree,
- Theodora Tryfona,
- Rita D. S. Marques,
- Sean T. Sweeney,
- Katrin Besser,
- Luisa Elias,
- Giovanna Pesante,
- Yi Li,
- Adam A. Dowle,
- Rachel Bates,
- Leonardo D. Gomez,
- Rachael Simister,
- Gideon J. Davies,
- Paul H. Walton,
- Neil C. Bruce,
- Simon J. McQueen-Mason
Affiliations
- Federico Sabbadin
- Centre for Novel Agricultural Products, Department of Biology, University of York
- Glyn R. Hemsworth
- School of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds
- Luisa Ciano
- Department of Chemistry, University of York
- Bernard Henrissat
- Architecture et Fonction des Macromolécules Biologiques (AFMB), UMR 7257 CNRS, Université Aix-Marseille
- Paul Dupree
- Department of Biochemistry, University of Cambridge
- Theodora Tryfona
- Department of Biochemistry, University of Cambridge
- Rita D. S. Marques
- Department of Biochemistry, University of Cambridge
- Sean T. Sweeney
- Department of Biology, University of York
- Katrin Besser
- Centre for Novel Agricultural Products, Department of Biology, University of York
- Luisa Elias
- Centre for Novel Agricultural Products, Department of Biology, University of York
- Giovanna Pesante
- Centre for Novel Agricultural Products, Department of Biology, University of York
- Yi Li
- Centre for Novel Agricultural Products, Department of Biology, University of York
- Adam A. Dowle
- Bioscience Technology Facility, Department of Biology, University of York
- Rachel Bates
- Bioscience Technology Facility, Department of Biology, University of York
- Leonardo D. Gomez
- Centre for Novel Agricultural Products, Department of Biology, University of York
- Rachael Simister
- Centre for Novel Agricultural Products, Department of Biology, University of York
- Gideon J. Davies
- Department of Chemistry, University of York
- Paul H. Walton
- Department of Chemistry, University of York
- Neil C. Bruce
- Centre for Novel Agricultural Products, Department of Biology, University of York
- Simon J. McQueen-Mason
- Centre for Novel Agricultural Products, Department of Biology, University of York
- DOI
- https://doi.org/10.1038/s41467-018-03142-x
- Journal volume & issue
-
Vol. 9,
no. 1
pp. 1 – 12
Abstract
LPMOs catalyze the oxidative breakdown of polysaccharides, thereby facilitating biomass degradation. By analyzing the digestive proteome of firebrats, the authors here identify a yet uncharacterized LPMO family and provide phylogenetic, structural and biochemical insights into its origin and functions.
