Современная ревматология (Dec 2013)
glucocorticoid osteoporosis; osteoporotic fracture; bisphosphonates; FRAX algorithm
Abstract
Glucocorticoids (GC) are extensively used to treat patients with systemic rheumatic diseases, which can improve their quality of life and substantially increase its span. At the same time their use is associated with the development of serious adverse reactions that cannot be always avoided. One of such complications is osteoporosis (OP) that gives rise to an increased risk for fractures. The paper gives recent clinical guidelines for the treatment and prevention of GC OP and the specific features of management in patients in relation to their age.