Biology (Apr 2021)

Neutron Source Based on Vacuum Insulated Tandem Accelerator and Lithium Target

  • Sergey Taskaev,
  • Evgenii Berendeev,
  • Marina Bikchurina,
  • Timofey Bykov,
  • Dmitrii Kasatov,
  • Iaroslav Kolesnikov,
  • Alexey Koshkarev,
  • Aleksandr Makarov,
  • Georgii Ostreinov,
  • Vyacheslav Porosev,
  • Sergey Savinov,
  • Ivan Shchudlo,
  • Evgeniia Sokolova,
  • Igor Sorokin,
  • Tatiana Sycheva,
  • Gleb Verkhovod

DOI
https://doi.org/10.3390/biology10050350
Journal volume & issue
Vol. 10, no. 5
p. 350

Abstract

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A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The proton beam energy can be varied within a range of 0.6–2.3 MeV, keeping a high-energy stability of 0.1%. The beam current can also be varied in a wide range (from 0.3 mA to 10 mA) with high current stability (0.4%). In the device, neutron flux is generated as a result of the 7Li(p,n)7Be threshold reaction. A beam-shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The BNCT technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China).

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