Human Vaccines & Immunotherapeutics (Oct 2018)

Update on trends in varicella mortality during the varicella vaccine era—United States, 1990–2016

  • Jessica Leung,
  • Mona Marin

DOI
https://doi.org/10.1080/21645515.2018.1480283
Journal volume & issue
Vol. 14, no. 10
pp. 2460 – 2463

Abstract

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We reported previously that the annual average mortality rate in the United States in 2008–2011 for varicella listed as the underlying cause declined 87% compared with the prevaccine period (1990–1994). Here, we update the analysis with five additional years of data. We used varicella death data from the 2012–2016 Mortality Multiple Cause-of Death records to calculate mortality rates during 2012–2016 and trends since the prevaccine period and end of 1-dose vaccination program (2005–2007). The annual average age-adjusted mortality rate for varicella as the underlying cause was 0.03 per million population during 2012–2016, a 94% reduction from prevaccine years and a 47% reduction from 2005–2007. Varicella deaths continue to decline due to the varicella vaccination program in the United States.

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