罕见病研究 (Oct 2023)

A Survey of the Current Status of Surgical Treatment of Hemophilic Osteoarthropathy in China Mainland 17 Grade A General Hospitals

  • XU Yiming,
  • PENG Huiming,
  • LYU Shuaijie,
  • TONG Peijian,
  • LI Hu,
  • CHEN Fenyong,
  • WANG Haibin,
  • YANG Qi,
  • CHEN Bin,
  • YUAN Zhen,
  • BI Rongxiu,
  • FENG Jianmin,
  • JIANG Wenxue,
  • ZHOU Zongke,
  • FAN Meng,
  • LI Xiang,
  • LEI Guanghua,
  • WENG Xisheng

DOI
https://doi.org/10.12376/j.issn.2097-0501.2023.04.008
Journal volume & issue
Vol. 2, no. 4
pp. 516 – 522

Abstract

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Objective To understand the current status of surgical treatment for hemophilia osteoarthropathy (HO) in China.Methods Using an online questionnaire, select domestic hospitals that partici-pated in the compilation of the 'Guideline for perioperative management of hemophilia patients undergoing orthopaedic surgery in China ', in addition to members of the National Joint Surgery Group, and the Orthopedic Branch of the Chinese Medical Association for targeted investigation and analysis.Results A total of 17 domestic hospitals were included, all of which were general hospitals. Hospitals that started HO surgery treatment before 2000 accounted for 35.29%. A total of 3057 surgical cases of HO were reported by those hospitals. The most commonly performed surgical procedures were hip and knee joint replacement. The most commonly used coagulation factor replacement regimen was recombinant coagulation factor preparation. Ten hospitals reported finding patients with transfusion-related infectious diseases. Bleeding and hematoma formation were the most frequently reported surgical complications. Excessive length of hospital stay and high economic costs were the most frequently reported problems.Conclusions Surgical treatment for HO in 17 hospitals is mainly carried out in some large comprehensive medical centers in the eastern region. Compared with the patient base, the popularity and number of surgeries are still relatively insufficient. It is necessary to further standardize the treatment system by standardizing factor replacement and strengthening rehabilitation to improve surgical treatment outcomes.

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