Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes

Xuemei Ge; Shang Wu; Wen Shen; Lijuan Chen; Yan Zheng; Fen Ao; Yuanlan Ning; Yueyang Mao; Zhong Chen

doi:10.3390/bioengineering9040130

Bioengineering (Mar 2022)

Preparation of Polyvinylidene Fluoride–Gold Nanoparticles Electrospinning Nanofiber Membranes

Xuemei Ge,
Shang Wu,
Wen Shen,
Lijuan Chen,
Yan Zheng,
Fen Ao,
Yuanlan Ning,
Yueyang Mao,
Zhong Chen

Affiliations

Xuemei Ge: Department of Food Science and Technology, College of Light Industry Science and Engineering, Nanjing Forestry University, Nanjing 210037, China
Shang Wu: School of Food and Bioengineering, Shaanxi University of Science and Technology, Xi’an 710021, China
Wen Shen: School of Food and Bioengineering, Shaanxi University of Science and Technology, Xi’an 710021, China
Lijuan Chen: Department of Food Science and Technology, College of Light Industry Science and Engineering, Nanjing Forestry University, Nanjing 210037, China
Yan Zheng: School of Food and Bioengineering, Shaanxi University of Science and Technology, Xi’an 710021, China
Fen Ao: School of Food and Bioengineering, Shaanxi University of Science and Technology, Xi’an 710021, China
Yuanlan Ning: School of Food and Bioengineering, Shaanxi University of Science and Technology, Xi’an 710021, China
Yueyang Mao: School of Food and Bioengineering, Shaanxi University of Science and Technology, Xi’an 710021, China
Zhong Chen: College of Biological and Pharmaceutical Engineering, Xinyang Agricultural and Forestry University, Xinyang 464000, China

DOI: https://doi.org/10.3390/bioengineering9040130
Journal volume & issue: Vol. 9, no. 4
p. 130

Abstract

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In this work, gold nanoparticles (AuNPs) and curcumin drug were incorporated in polyvinylidene fluoride (PVDF) nanofibers by electrospinning as a novel tissue engineering scaffold in nerve regeneration. The influence of AuNPs on the morphology, crystallinity, and drug release behavior of nanofiber membranes was characterized. A successful composite nanofiber membrane sample was observed by scanning electron microscopy (SEM). The addition of AuNPs showed the improved as well as prolonged cumulative release of the drug. The results indicated that PVDF–AuNPs nanofiber membrane could potentially be applied for nerve regeneration.

Published in Bioengineering

ISSN: 2306-5354 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Technology; Science: Biology (General)
Website: https://www.mdpi.com/journal/bioengineering

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