Nature Communications (Feb 2019)
Multi-cohort study identifies social determinants of systemic inflammation over the life course
- Eloïse Berger,
- Raphaële Castagné,
- Marc Chadeau-Hyam,
- Murielle Bochud,
- Angelo d’Errico,
- Martina Gandini,
- Maryam Karimi,
- Mika Kivimäki,
- Vittorio Krogh,
- Michael Marmot,
- Salvatore Panico,
- Martin Preisig,
- Fulvio Ricceri,
- Carlotta Sacerdote,
- Andrew Steptoe,
- Silvia Stringhini,
- Rosario Tumino,
- Paolo Vineis,
- Cyrille Delpierre,
- Michelle Kelly-Irving
Affiliations
- Eloïse Berger
- LEASP, UMR 1027, Inserm-Université Toulouse III Paul Sabatier
- Raphaële Castagné
- LEASP, UMR 1027, Inserm-Université Toulouse III Paul Sabatier
- Marc Chadeau-Hyam
- MRC-PHE Centre for Environment and Health, School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London
- Murielle Bochud
- Psychiatric Epidemiology and Psychopathology Center, Department of Psychiatry, Lausanne University Hospital
- Angelo d’Errico
- Epidemiology Unit, ASL TO3 Piedmont Region
- Martina Gandini
- Epidemiology Unit, ASL TO3 Piedmont Region
- Maryam Karimi
- MRC-PHE Centre for Environment and Health, School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London
- Mika Kivimäki
- Department of Epidemiology and Public Health, University College London
- Vittorio Krogh
- Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori
- Michael Marmot
- Department of Epidemiology and Public Health, University College London
- Salvatore Panico
- Department of Clinical Medicine and Surgery, University of Naples Federico II
- Martin Preisig
- Psychiatric Epidemiology and Psychopathology Center, Department of Psychiatry, Lausanne University Hospital
- Fulvio Ricceri
- Epidemiology Unit, ASL TO3 Piedmont Region
- Carlotta Sacerdote
- Piedmont Reference Centre for Epidemiology and Cancer Prevention (CPO Piemonte)
- Andrew Steptoe
- Department of Epidemiology and Public Health, University College London
- Silvia Stringhini
- Institute of Social and Preventive Medicine, Lausanne University Hospital
- Rosario Tumino
- Cancer Registry and Histopathology Department, ‘Civic – M. P. Arezzo’ Hospital, ASP Ragusa
- Paolo Vineis
- MRC-PHE Centre for Environment and Health, School of Public Health, Department of Epidemiology and Biostatistics, Imperial College London
- Cyrille Delpierre
- LEASP, UMR 1027, Inserm-Université Toulouse III Paul Sabatier
- Michelle Kelly-Irving
- LEASP, UMR 1027, Inserm-Université Toulouse III Paul Sabatier
- DOI
- https://doi.org/10.1038/s41467-019-08732-x
- Journal volume & issue
-
Vol. 10,
no. 1
pp. 1 – 10
Abstract
Here, the authors explore the relationship between socioeconomic position (SEP) across the life course and inflammation in a multi-cohort study and show that educational attainment is most strongly related to inflammation, suggesting that socioeconomic disadvantage in young adulthood is independently associated with later life inflammation.
