JACC: Case Reports (Feb 2024)

Sequential Alcohol Septal Ablation to Resolve LV Outflow Tract Obstruction After Transcatheter Mitral Valve Replacement

  • Mark M.P. van den Dorpel, MD,
  • Mauricio Felippi de Sá Marchi, MD,
  • Sarah Verhemel, MD,
  • Rik Adrichem, MD,
  • Rutger-Jan Nuis, MD, PhD,
  • Joost Daemen, MD, PhD,
  • Marcel L. Geleijnse, MD, PhD,
  • Claire Ben Ren, MD, PhD,
  • Alexander Hirsch, MD, PhD,
  • Nicolas M. Van Mieghem, MD, PhD

Journal volume & issue
Vol. 29, no. 3
p. 102193

Abstract

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Left ventricular outflow tract obstruction (LVOTO) is a notorious complication of transcatheter mitral valve replacement (TMVR). Computed tomography–derived simulations can predict neo-LVOTO post-TMVR, whereas alcohol septal ablation can mitigate neo-LVOTO risk. We report a case of sequential alcohol septal ablation of 2 adjacent septal branches to resolve unexpected neo-LVOTO post-TMVR.

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