Open Medicine (Aug 2024)
Reproductive outcomes in women with BRCA 1/2 germline mutations: A retrospective observational study and literature review
- Dellino Miriam,
- D’Amato Antonio,
- Battista Gaia,
- Cormio Gennaro,
- Vimercati Antonella,
- Loizzi Vera,
- Laganà Antonio Simone,
- Damiani Gianluca Raffaello,
- Favilli Alessandro,
- Gerli Sandro,
- La Forgia Daniele,
- Daniele Antonella,
- Agrifoglio Vittorio,
- Cicinelli Ettore,
- Vitagliano Amerigo,
- Etrusco Andrea
Affiliations
- Dellino Miriam
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- D’Amato Antonio
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- Battista Gaia
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- Cormio Gennaro
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- Vimercati Antonella
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- Loizzi Vera
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- Laganà Antonio Simone
- Unit of Obstetrics and Gynecology, “Paolo Giaccone” Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127Palermo, Italy
- Damiani Gianluca Raffaello
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- Favilli Alessandro
- Department of Medicine and Surgery, University of Perugia, 06132Perugia, Italy
- Gerli Sandro
- Department of Medicine and Surgery, University of Perugia, 06132Perugia, Italy
- La Forgia Daniele
- Department of Gynecology and Obstetrics, Istituto Tumori Giovanni Paolo II, I.R.C.C.S, 70124Bari, Italy
- Daniele Antonella
- Department of Gynecology and Obstetrics, Istituto Tumori Giovanni Paolo II, I.R.C.C.S, 70124Bari, Italy
- Agrifoglio Vittorio
- Unit of Obstetrics and Gynecology, “Paolo Giaccone” Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127Palermo, Italy
- Cicinelli Ettore
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- Vitagliano Amerigo
- Department of Biomedical Sciences and Human Oncology, Obstetrics and Gynecology Unit, University of Bari “Aldo Moro”, 70124Bari, Italy
- Etrusco Andrea
- Unit of Obstetrics and Gynecology, “Paolo Giaccone” Hospital, Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties (PROMISE), University of Palermo, 90127Palermo, Italy
- DOI
- https://doi.org/10.1515/med-2024-9999
- Journal volume & issue
-
Vol. 19,
no. 1
pp. 139 – 53
Abstract
Despite evidence indicating a decrease in ovarian reserve among BRCA patients, this factor seems to not impact their spontaneous fertility negatively.
Keywords