First cases of DENV-3 circulation in the Casanare region of Colombia

Abstract

Dengue is a viral infection found in tropical and subtropical areas. It has four serotypes: DENV-1, DENV-2, DENV-3 and DENV-4. In the last 50 years the incidence of dengue has increased throughout the world. The first three cases with isolation of DENV-3 in the Casanare region, Colombia are presented: an adult woman and two children. Of the latter: a 6-year-old girl and a 7-month-old boy; which shared clinical characteristics, such as fever and abdominal pain. The first case presented rapid remission, with dengue with warning signs, and the children with severe dengue. The girl progressed adequately, but the 7-month-old boy with severe dengue died. The introduction of a new serotype into areas affected by preexisting serotypes constitutes a risk factor for dengue with warning signs and severe dengue.

Keywords

• virus del dengue
• trombocitopenia
• leucopenia
• dengue grave
• serositis
• derrame pleural