A Giant Posterior Mediastinal Metastatic Mass of GIST Gastric Origin

Abstract

Gastrointestinal stromal tumors (GISTs) are uncommon visceral sarcomas that predominantly arise from the gastrointestinal tract, particularly from interstitial cells of Cajal. Although the liver is a common site for metastasis, rarely GISTs show extraintestinal manifestation in the bone and lungs. We report a case patient with an uncommon location and unusually large GIST metastasis as a mediastinal mass 3 years after undergoing total gastrectomy and chemotherapy with imatinib, a tyrosine kinase inhibitor.