Bond Strength of Adhesive Systems to Calcium Silicate-Based Materials: A Systematic Review and Meta-Analysis of In Vitro Studies
Louis Hardan,
Davide Mancino,
Rim Bourgi,
Alejandra Alvarado-Orozco,
Laura Emma Rodríguez-Vilchis,
Abigailt Flores-Ledesma,
Carlos Enrique Cuevas-Suárez,
Monika Lukomska-Szymanska,
Ammar Eid,
Maya-Line Danhache,
Maryline Minoux,
Youssef Haïkel,
Naji Kharouf
Affiliations
Louis Hardan
Department of Restorative Dentistry, School of Dentistry, Saint-Joseph University, Beirut 1107 2180, Lebanon
Davide Mancino
Department of Biomaterials and Bioengineering, INSERM UMR_S 1121, Biomaterials and Bioengineering, 67000 Strasbourg, France
Rim Bourgi
Department of Restorative Dentistry, School of Dentistry, Saint-Joseph University, Beirut 1107 2180, Lebanon
Alejandra Alvarado-Orozco
Centro de Investigación y Estudios Avanzados en Odontología, Facultad de Odontología, Universidad Autónoma del Estado de México, Jesús Carranza esq. Paseo Tollocan, Col. Universidad, Toluca 50130, Mexico
Laura Emma Rodríguez-Vilchis
Centro de Investigación y Estudios Avanzados en Odontología, Facultad de Odontología, Universidad Autónoma del Estado de México, Jesús Carranza esq. Paseo Tollocan, Col. Universidad, Toluca 50130, Mexico
Abigailt Flores-Ledesma
Facultad de Estomatología, Benemerita Universidad Autónoma de Puebla, 31 Poniente #1304, Colonia Volcanes, Puebla 72410, Mexico
Carlos Enrique Cuevas-Suárez
Dental Materials Laboratory, Academic Area of Dentistry, Autonomous University of Hidalgo State, Circuito Ex Hacienda La Concepción S/N, San Agustín Tlaxiaca 42160, Mexico
Monika Lukomska-Szymanska
Department of General Dentistry, Medical University of Lodz, 251 Pomorska St., 92-213 Lodz, Poland
Ammar Eid
Department of Endodontics, Faculty of Dental Medicine, Damascus University, Damascus 0100, Syria
Maya-Line Danhache
Department of Stomatology, Robert-Debré Hospital, 75019 Paris, France
Maryline Minoux
Department of Endodontics, Faculty of Dental Medicine, Strasbourg University, 67000 Strasbourg, France
Youssef Haïkel
Department of Biomaterials and Bioengineering, INSERM UMR_S 1121, Biomaterials and Bioengineering, 67000 Strasbourg, France
Naji Kharouf
Department of Biomaterials and Bioengineering, INSERM UMR_S 1121, Biomaterials and Bioengineering, 67000 Strasbourg, France
Since the adhesion of resin composites to calcium silicate-based cement is considered challenging. Therefore, the best adhesion strategy should be indicated. This review aimed to assess the effect of different adhesive systems on the bond strength of resin composite to calcium silicate-based cement through a systematic review and meta-analysis. The subsequent PICOS framework used was: population, calcium silicate-based cement; intervention, use of self-etch adhesive systems; control, use of total-etch adhesive systems; outcome, bond strength; study design, in vitro studies. The literature search was conducted independently by two reviewers up to 18 February 2021. Electronic databases (PubMed, ISI Web of Science, SciELO, Scopus, and Embase) were searched for applicable articles. In vitro manuscripts studying the effect of adhesive systems on the bond strength of calcium silicate-based cement were considered. The meta-analyses were performed using Review Manager Software version 5.3.5 (The Nordic Cochrane Centre, The Cochrane Collaboration, Copenhagen, Denmark). Bond strength comparisons were made considering the type of calcium silicate-based cement (Mineral Trioxide Aggregate (MTA), Biodentine™, or TheraCal LC®). A p-value ® cement were favored when a total-etch adhesive system was used (p ≤ 0.02). On the other hand, the meta-analysis of the bond strength of resin-based materials to Biodentine™ calcium silicate-based cement was similar between both approaches (p = 0.12). The in vitro evidence suggests that the bond strength of resin-based materials to both MTA and TheraCal LC® cement was preferred by using the total-etch adhesive strategy. However, when bonding to Biodentine™, the use of self-etch or total-etch strategies displayed promising results. Given the lack of evidence related to the chemical interaction of self-etch adhesive materials with the bioceramics, if self-etch adhesives are used for bonding resin-based restorations to calcium silicate-based cement, a pretreatment with phosphoric acid could be recommended.