Subcortical Band Heterotopia Syndrome in children - comparison of two case reports

Abstract

This article aims to present the cases of two pediatric patients with Subcortical Band Heterotopia, monitored in our clinic over a period of one year with respect to seizure frequency and cognitive as well as behavioral evolution. While one of the patients was born at 32 weeks and had a delay in reaching the normal developmental milestones, the second patient had no significant history of psychomotor delay. Both patients showed epileptic seizures, one of them evolving to intractable epilepsy, mild cognitive decline and behavioral problems, while the other presented a wide seizure-free interval and no cognitive impairment. Finally, we would like to emphasize that in a child with epilepsy and psychomotor delay, with an evocative EEG, cortical development disorders should be considered and magnetic resonance imaging (MRI) should be carried out.

Keywords

• subcortical band heterotopia
• epilepsy
• cognitive impairment
• children