SAGE Open Medical Case Reports (May 2024)

Efficacy of nature killer cell combination chemotherapy for post-radical gastric cancer metastases: Case report

  • Yongting Yue,
  • Mengmeng Zi,
  • Jianing Feng,
  • Wenbang Wang,
  • Zhaoqi Ren,
  • Chuntao Wu,
  • Zhaoyong Yang

DOI
https://doi.org/10.1177/2050313X241254743
Journal volume & issue
Vol. 12

Abstract

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Nature killer cell therapy has shown strong efficacy in the field of oncology in recent years and has been applied to patients with metastases with the aim of improving the prognosis of advanced gastric cancer. A 59-year-old male with gastric adenocarcinoma with pancreatic metastasis (T4N0M1) who underwent radical surgery for gastric cancer with tumor metastasis was treated with oxaliplatin and tegafur combined with cellular reinfusion in stages. Computed tomograpy scan and serum tumor markers were monitored continuously after the treatment course. After five courses of combined treatment, the patient was in disease control with no significant side effects. At the last follow-up, the alpha fetoprotein had returned to its normal value with a poor display of low-density shadows in the body of the pancreas. Pancreatic cancer is insidious in origin and has a high mortality rate. The report provides clinical evidence for cell therapy of pancreatic metastatic cancer with improved quality of life.