G6PD functions as a metabolic checkpoint to regulate granzyme B expression in tumor-specific cytotoxic T lymphocytes

• Chunwan Lu,
• Kebin Liu,
• John D Klement,
• Dafeng Yang,
• Huidong Shi,
• Yolonda L Colson,
• Nicholas H Oberlies,
• Cedric J Pearce,
• Aaron H Colby,
• Mark W Grinstaff,
• Han-Fei Ding

Affiliations

Chunwan Lu

Aff1 Department of Biochemistry and Molecular Biology Medical College of Georgia 30912 Augusta GA USA

Kebin Liu

Aff1 Department of Biochemistry and Molecular Biology Medical College of Georgia 30912 Augusta GA USA

John D Klement

Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States

Dafeng Yang

Department of Biochemistry and Molecular Biology, Augusta University, Augusta, Georgia, United States

Huidong Shi

Georgia Cancer Center, Medical College of Georgia, Augusta, Georgia, USA

Yolonda L Colson

Division of Thoracic Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

Nicholas H Oberlies

Department of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, NC, USA

Cedric J Pearce

Mycosynthetix Inc, Hillsborough, NC, USA

Aaron H Colby

Ionic Pharmaceuticals, Brookline, MA, USA

Mark W Grinstaff

Ionic Pharmaceuticals, Brookline, MA, USA

Han-Fei Ding

Georgia Cancer Center, Medical College of Georgia, Augusta, GA, USA