Development, preparation and characterization of chitosan, gelatin and heparin membranes for biomedical applications

Abstract

Abstract With the rising in life expectancy and the consequent population aging, degenerative chronic diseases have been figured as the major cause of morbidity and mortality in the world. It is believed that the production of a polymeric matrix composed of chitosan and gelatin may be an alternative to obtain a carrier base of heparin, with the prospective objective of applying these materials as an alternative to the conventional therapeutic resources biomedical. Based on the results, it can be concluded that the interaction between chitosan, gelatin, and heparin demonstrating a satisfactory result by the methodologies that were applied, making the study hypothesis concrete., certifying the use of a methodology for including heparin in a biodegradable polymeric base. Thus, expanding the alternatives for possible alternatives to the conventional therapeutic resources of vascular diseases with the application of the developed materials.

Keywords

• Heparin
• Gelatine
• Chitosan
• Membranes
• Biomaterials