Advanced Science (Apr 2023)

Stretchable and Skin‐Attachable Electronic Device for Remotely Controlled Wearable Cancer Therapy

  • Xiaohui Ma,
  • Xiaotong Wu,
  • Shitai Cao,
  • Yinfeng Zhao,
  • Yong Lin,
  • Yurui Xu,
  • Xinghai Ning,
  • Desheng Kong

DOI
https://doi.org/10.1002/advs.202205343
Journal volume & issue
Vol. 10, no. 10
pp. n/a – n/a

Abstract

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Abstract Surgery represents a primary clinical treatment of solid tumors. The high risk of local relapse typically requires frequent hospital visits for postoperative adjuvant therapy. Here, device designs and system integration of a stretchable electronic device for wearable cancer treatment are presented. The soft electronic patch harnesses compliant materials to achieve conformal and stable attachment to the surgical wound. A composite nanotextile dressing is laminated to the electronic patch to allow the on‐demand release of anticancer drugs under electro‐thermal actuation. An additional flexible circuit and a compact battery complete an untethered wearable system to execute remote therapeutic commands from a smartphone. The successful implementation of combined chemothermotherapy to inhibit tumor recurrence demonstrates the promising potential of stretchable electronics for advanced wearable therapies without interfering with daily activities.

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