Idiopathic dendriform pulmonary ossification diagnosed only after a surgical biopsy: A case report

Tomohito Takeshige; Ryo Koyama; Eisuke Goto; Tatsuo Maeyashiki; Akifumi Okajima; Toshihiko Nishioki; Junko Watanabe; Toshifumi Yae; Takamitsu Banno; Kenji Kido; Kazuhisa Takahashi

doi:10.1016/j.rmcr.2025.102227

Respiratory Medicine Case Reports (Jan 2025)

Idiopathic dendriform pulmonary ossification diagnosed only after a surgical biopsy: A case report

Tomohito Takeshige,
Ryo Koyama,
Eisuke Goto,
Tatsuo Maeyashiki,
Akifumi Okajima,
Toshihiko Nishioki,
Junko Watanabe,
Toshifumi Yae,
Takamitsu Banno,
Kenji Kido,
Kazuhisa Takahashi

Affiliations

Tomohito Takeshige: Department of Respiratory Medicine, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan; Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, 3-1-3, Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan; Corresponding author. Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.
Ryo Koyama: Department of Respiratory Medicine, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Eisuke Goto: Department of Thoracic Surgery, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Tatsuo Maeyashiki: Department of Thoracic Surgery, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Akifumi Okajima: Department of Respiratory Medicine, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Toshihiko Nishioki: Department of Respiratory Medicine, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Junko Watanabe: Department of Respiratory Medicine, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Toshifumi Yae: Department of Respiratory Medicine, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Takamitsu Banno: Department of Thoracic Surgery, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Kenji Kido: Department of Respiratory Medicine, Juntendo University Nerima Hospital, 3-1-1, Takanodai, Nerima-ku, Tokyo, 177-8521, Japan
Kazuhisa Takahashi: Department of Respiratory Medicine, Juntendo University Faculty of Medicine and Graduate School of Medicine, 3-1-3, Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan

DOI: https://doi.org/10.1016/j.rmcr.2025.102227
Journal volume & issue: Vol. 55
p. 102227

Abstract

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Idiopathic dendriform pulmonary ossification (IDPO) presents as dendritic ossification of the lungs without a particular cause. IDPO is often diagnosed using surgical biopsy, transbronchial lung biopsy (TBLB), or transbronchial lung cryobiopsy (TBLC). In this case report, we described a 36-year-old male who presented with abnormal chest findings radiographically. TBLB was performed but no diagnosis was made. Instead, IDPO was diagnosed following a surgical biopsy. CT tomography and respiratory function tests showed no progression over the past 3.5 years. However, a nationwide survey in Japan revealed several cases of disease progression. Considering this, careful monitoring of the disease is recommended.

Published in Respiratory Medicine Case Reports

ISSN: 2213-0071 (Online)
Publisher: Elsevier
Country of publisher: Netherlands
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the respiratory system
Website: https://www.sciencedirect.com/journal/respiratory-medicine-case-reports

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