International Journal of Clinical Practice (Jan 2024)

Circulating FGF-23 Is Associated With Increased Risk of Osteoporosis and Fractures in Hemodialysis Patients: A Prospective Observational Study

  • Dong Liu,
  • Hongyan Yang,
  • Qirong Liao,
  • Baocao Chang,
  • Weiwei Zhang,
  • Xiaoxiong Li,
  • Jinping Li,
  • Mingliang Hou,
  • Linqiu Ma,
  • Yating Liu,
  • Jing Lu,
  • Rui Zhou

DOI
https://doi.org/10.1155/2024/1070492
Journal volume & issue
Vol. 2024

Abstract

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Conclusion: High concentrations of circulating FGF-23 were associated with the risk of osteoporosis and fractures, including vertebral fractures and hip fractures. FGF-23, along with bALP, CTX, and OC, may be used as a serum biomarker for predicting the risk of osteoporosis and fractures in patients with hemodialysis.