Frontiers in Physiology (Apr 2019)

Xenopus Resources: Transgenic, Inbred and Mutant Animals, Training Opportunities, and Web-Based Support

  • Marko Horb,
  • Marcin Wlizla,
  • Anita Abu-Daya,
  • Sean McNamara,
  • Dominika Gajdasik,
  • Takeshi Igawa,
  • Atsushi Suzuki,
  • Hajime Ogino,
  • Anna Noble,
  • Centre de Ressource Biologique Xenope team in France,
  • Jacques Robert,
  • Christina James-Zorn,
  • Matthew Guille,
  • Matthew Guille,
  • Morgane Nicolas,
  • Thomas Lafond,
  • Daniel Boujard,
  • Yann Audic,
  • Brigitte Guillet

DOI
https://doi.org/10.3389/fphys.2019.00387
Journal volume & issue
Vol. 10

Abstract

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Two species of the clawed frog family, Xenopus laevis and X. tropicalis, are widely used as tools to investigate both normal and disease-state biochemistry, genetics, cell biology, and developmental biology. To support both frog specialist and non-specialist scientists needing access to these models for their research, a number of centralized resources exist around the world. These include centers that hold live and frozen stocks of transgenic, inbred and mutant animals and centers that hold molecular resources. This infrastructure is supported by a model organism database. Here, we describe much of this infrastructure and encourage the community to make the best use of it and to guide the resource centers in developing new lines and libraries.

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