Acta Pharmaceutica (Sep 2015)

Contribution to diagnostics/prognostics of tuberculosis in children. II. Indicative value of metal ions and biochemical parameters in serum

  • Luterotti Svjetlana,
  • Kordić Tončica Vukman,
  • Letoja Ivka Zoričić,
  • Dodig Slavica

DOI
https://doi.org/10.1515/acph-2015-0027
Journal volume & issue
Vol. 65, no. 3
pp. 321 – 329

Abstract

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Newly introduced methods of assaying simultaneously copper and zinc and zinc alone in serum by flame atomic-absorption spectrometry are simple and economical, especially in saving the consumption of serum material. Along with biochemical parameters, they have been successfully applied to diagnostics/prognostics of tuberculosis in children, through analyses of sera from pediatric patients with lung tuberculosis or suspected tuberculosis, enabling the follow-up of therapeutic efficiency. The prognostic strength of Cu and Cu/Zn ratio together with C-reactive protein, complement components C3 and C4, and erythrocyte sedimentation rate have been documented.

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