The Role of Different Inflammatory Indices in the Diagnosis of COVID-19

Abstract

Marwa Eissa,1,2 Sabry Shaarawy,3 Mona S Abdellateif3 1Internal Medicine and Endocrinology Department, Faculty of Medicine, Cairo University, Cairo, Egypt; 2Endocrinology Department, Faculty of Armed Forces of Medical College (AFMC), Cairo, Egypt; 3Medical Biochemistry and Molecular Biology, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, EgyptCorrespondence: Mona S AbdellateifMedical Biochemistry and Molecular Biology, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, 11976, EgyptFax + 202 23644720Email [email protected]: To assess the role of different inflammatory indices in the diagnosis of COVID-19 infection.Methods: The neutrophil-to-lymphocyte ratio (NLR), lymphocyte-to-monocyte ratio (LMR), platelet-to-lymphocyte ratio (PLR), derived NLR (dNLR), neutrophil to lymphocyte, platelet ratio (NLPR), systemic inflammation index (SII), aggregate index of systemic inflammation (AISI), systemic inflammation response index (SIRI) and C-reactive protein-to-lymphocyte ratio (CRP/L) were assessed in 88 COVID-19 patients compared to 41 healthy control subjects.Results: The NLR, PLR, NLPR, SIRI, and CRP/L were significantly increased, while LMR was significantly decreased in COVID-19 patients compared to the control group (P = 0.008, 0.011, 0.011 (OR: 38.751, P = 0.014), and CRP/L > 7.6 (OR: 7.604, P = 0.022) are possible independent diagnostic factors for COVID-19 infection.Conclusion: NLPR and CRP/L could be potential independent diagnostic factors for COVID-19 infection.Keywords: COVID-19, C-reactive protein, lymphocytes, inflammatory index, platelets, SII

Keywords

• covid-19
• c-reactive protein
• lymphocytes
• inflammatory index
• platelets
• sii.