High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan

Ying-Chi Huang; Jui-Fen Lai; Chi-Jung Wu; I-Wen Huang; Shu-Chen Kuo; Ching-Len Liao; Tzu-Wen Huang; Tsai-Ling Lauderdale

Journal of Microbiology, Immunology and Infection (Aug 2023)

High-level levofloxacin-resistant emm12 group A Streptococcus, 2012–2018: A multicenter study in Taiwan

Ying-Chi Huang,
Jui-Fen Lai,
Chi-Jung Wu,
I-Wen Huang,
Shu-Chen Kuo,
Ching-Len Liao,
Tzu-Wen Huang,
Tsai-Ling Lauderdale

Affiliations

Ying-Chi Huang: National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan
Jui-Fen Lai: National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan
Chi-Jung Wu: National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan; Department of Internal Medicine, National Cheng Kung University Hospital, National Cheng Kung University, Tainan, Taiwan
I-Wen Huang: National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan
Shu-Chen Kuo: National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan
Ching-Len Liao: National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan
Tzu-Wen Huang: Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Corresponding author. Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University; Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei 11031, Taiwan.
Tsai-Ling Lauderdale: National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Zhunan, Taiwan; Corresponding author. National Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, No.35, Keyan Road, Zhunan, Miaoli County 35053, Taiwan.

Journal volume & issue: Vol. 56, no. 4
pp. 875 – 879

Abstract

Read online

High-level levofloxacin-resistant group A Streptococcus emerged in Taiwan in 2012. Among the 24 isolates identified, 23 belonged to emm12/ST36, most harbored the same GyrA and ParC mutations and were highly clonal. wgMLST showed them to be closely related to the Hong Kong scarlet fever outbreak strains. Continuous surveillance is warranted.

Published in Journal of Microbiology, Immunology and Infection

ISSN: 1684-1182 (Print)
Publisher: Elsevier
Country of publisher: Hong Kong
LCC subjects: Science: Microbiology
Website: https://www.sciencedirect.com/journal/journal-of-microbiology-immunology-and-infection

About the journal

Abstract

Keywords