Frontiers in Oncology (Jul 2023)

New treatment insights into pancreatic acinar cell carcinoma: case report and literature review

  • Fangrui Zhao,
  • Dashuai Yang,
  • Tangpeng Xu,
  • Jiahui He,
  • Jin Guo,
  • Xiangpan Li

DOI
https://doi.org/10.3389/fonc.2023.1210064
Journal volume & issue
Vol. 13

Abstract

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Pancreatic acinar cell carcinoma (PACC) is a rare pancreatic malignancy with unique clinical, molecular, and morphologic features. The long-term survival of patients with PACC is substantially better than that of patients with ductal adenocarcinoma of the pancreas. Surgical resection is considered the first choice for treatment; however, there is no standard treatment option for patients with inoperable disease. The patient with metastatic PACC reported herein survived for more than 5 years with various treatments including chemotherapy, radiotherapy, antiangiogenic therapy and combined immunotherapy.

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