Application of SSIR Method for the Design of Fungicides

Abstract

The design of fungicides is a central topic in agricultural chemistry. In this manuscript, it is shown how the Superposition of Significant Interaction Rules (SSIR) method can serve the generation of new potentially active molecules. By using SSIR, it is shown how the process becomes a simple symbolic procedure without the intervention of sophisticated statistical methods, although the results obtained are comparable.

Keywords

• QSAR
• drug design
• agro-chemistry
• fungicides
• SSIR method